Validity tab. №10

Pharmacological effect

The effect of the drug is largely due to reflex reactions associated with irritation of sensitive nerve endings. Validol is close to menthol. Validol has a moderate reflex vasodilator effect, has a sedative effect (sedative effect on the central nervous system). Irritation of mucous membrane receptors is accompanied by stimulation of the formation and release of enkephalins, endorphins, dynorphins and peptides, which play an important role in regulating pain, vascular permeability and other processes.

Under the influence of irritating substances, several other endogenous physiologically active compounds (histamine, kinins, etc.) are released. With sublingual administration, the effect of the drug appears after 5 minutes.

Indications

neurosis;

hysteria, hysterical states;

Angina attacks (as part of combined treatment);

heart-type neuro-circulatory dystonia, functional cardialgia;

as an antiemetic for seaborne and airborne diseases.