For the most noticeable effect, apply the serum while your face is still slightly damp after cleansing — hyaluronic acid works by attracting and holding water near the skin surface, so giving it moisture to bind to makes a real difference. Use a few drops and press them gently over the face and neck. Wait about 30–60 seconds for the liquid to absorb, then follow with a cream or lotion. The moisturizer creates a barrier that slows evaporation from the upper layers, which is what keeps the skin looking smoother and more elastic through the day. If you apply the serum on completely dry skin in a low-humidity environment (heated indoor air, airplane cabin), it can pull moisture from deeper layers instead, which may leave the face feeling tighter. The liquid texture absorbs quickly and does not leave a sticky film, so it layers well under both day and night creams.