Because this is a light cream with a dry-touch finish, it layers well under or over most other foot products. A practical order after washing and drying: first apply any prescribed or pharmacy treatment (antifungal cream, wart treatment, etc.) and let it absorb fully; then apply the Fitodoktor cream for moisture management and comfort; finally, if you use a foot powder for extra dryness, dust it on once the cream has set. If you like a richer balm for very rough heels at night, you can apply the balm over this cream or use the balm on alternate evenings.
Avoid combining with strong exfoliating acids (salicylic, glycolic, urea above 10%) on the same area at the same time unless a specialist has advised it — the astringent effect of oak bark may increase irritation risk. Sunscreen is not needed on the soles, but if you apply the cream to the tops of feet before open sandals, follow with SPF. Store the tube at room temperature, cap closed, and use within the period-after-opening indicated on the packaging (typically 12 months).