This product contains bee venom — the source calls it apitoxin from Apis mellifera — so it is not suitable for anyone with a known allergy to bee stings, bee venom or bee products. If you have had any previous reaction to bee stings or bee-based cosmetics, do not use it. If you are unsure whether you are allergic, a patch test is the safest way to start.
To do a patch test, apply a small amount to a small area of intact skin — the inside of the forearm is a practical spot — and wait at least 24 hours to see if any redness, itching, burning or other reaction develops. This is essential before the first use, even if you do not think you have an allergy. The warming sensation can feel intense, but it should not be painful. If you feel marked irritation, stinging or an unusual reaction, wash the area with mild soap and water and stop using the product.
For sensitive skin in general, start with a smaller amount than you think you need, and avoid using the gel on areas that are already irritated, sunburned, scratched or affected by eczema or other skin conditions. You should also avoid the eyes, mouth and all mucous membranes. If the product accidentally gets into the eyes, rinse thoroughly with water. Because this is a cosmetic, it is not a treatment for allergies or skin conditions, and persistent discomfort should be checked by a doctor.