The formula contains rose extract, licorice extract, chicory extract, and fragrance, which are potential sensitizers for some individuals with reactive skin. The product instructions explicitly advise that if you are sensitive to fragrance, menthol, or any plant extracts, you should patch test first and stop use if irritation appears. To perform a patch test, apply a small amount of serum to a discreet area of skin on your inner forearm or behind your ear. Leave it on for 24-48 hours and monitor for any redness, itching, or discomfort. Furthermore, the directions state the serum is best suited for the mid-lengths and ends of the hair, not the scalp area. This application guideline itself helps minimize skin contact. When using the product, take care to apply it only to your hair lengths, avoiding the scalp, hairline, forehead, neck, and any areas where the serum might transfer from your hair to your skin during the day. If you have a history of contact dermatitis or very sensitive skin, you may want to consult with a dermatologist before incorporating any new cosmetic product into your routine. Always discontinue use immediately if you experience any signs of irritation.