How should I apply this cream for the best results on very dry or rough areas?

For the most effective barrier effect, apply the cream while your skin is still slightly damp after washing — this helps the glycerine bind water in the upper layers before the petrolatum seals it in. Use a thin, even layer; a little goes a long way because the formula is rich and occlusive. Pay extra attention to areas that tend to get rough or tight: elbows, knees, heels, hands, and any patches exposed to cold wind or indoor heating. If you shower twice a day, once-daily application (usually after the evening shower) is often enough; reapply on specific spots whenever they feel dry again. The cream absorbs slowly by design — the surface film is what reduces water loss — so allow a few minutes before dressing if you prefer a less tacky feel.

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