This cream can be used as the moisturising step after lighter products such as toners or serums. If you already use a niacinamide serum, you do not necessarily need both; using niacinamide in a moisturiser may be enough if your goal is a simpler routine focused on hydration, barrier support and a more balanced-looking complexion.
With exfoliating acids or retinoids, the main point is skin tolerance. The product description notes that reactive skin should introduce any new cream gradually, especially alongside strong active products. A practical approach is to keep your active product on its usual schedule and add this cream once daily at first. If the combination feels comfortable, you can move to morning and evening use. If the skin starts to sting, feel hot, peel excessively or become persistently red, simplify the routine for a few days.
For daytime use, apply the cream before sunscreen. Let it settle briefly before makeup, especially if you use foundation or concealer, because applying layers too quickly can sometimes cause pilling. If pilling happens, try using less cream, waiting longer between steps, or reducing the number of products underneath.